Tetrahydroquinoline is an organic compound with the chemical name 1,2,3,4-tetrahydroquinoline. It has a molecular formula of C9H11N, a molecular weight of 133.19, and a CAS number of 635-46-1. This substance has a density of 1.0 ± 0.1 g/cm³, a boiling point of 250.8 ± 10.0 °C (at standard pressure), and a melting point of 9–14 °C. It appears as a colorless, transparent, or pale yellow liquid, and its water solubility at room temperature is less than 1 g/L (at 20 °C).
It can be synthesized via the hydrogenation of quinoline catalyzed by a nano-Pd/mesoporous graphitic carbon nitride (mpg-C3N4) catalyst; under conditions of 30–50 °C and a hydrogen pressure of 0.1 MPa, this process achieves nearly 100% conversion and selectivity. This compound is primarily utilized in the field of organic synthesis. For storage, it should be kept tightly sealed in a cool, dry environment, away from oxidizing agents. According to GHS classification standards, this substance carries hazard labels indicating skin and eye irritation/respiratory tract irritation (H315/H319/H335) as well as carcinogenicity (H350).
